Loss of the chromosomal region 5q11-q31 in the myeloid cell line HL-60: Characterization by comparative genomic hybridization and fluorescence in situ hybridization

Characterization of the human myeloid le

Characterization of the human myeloid leukemia-derived cell line GF-D8 by multiplex fluorescence in situ hybridization, subtelomeric probes, and comparative genomic hybridization

✍ Sabrina Tosi; Giovanni Giudici; Alessandro Rambaldi; Stephen W. Scherer; Patrici 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 401 KB 👁 2 views

The human myeloid leukemia cell line GF-D8 was established from the peripheral blood blasts of a patient with acute myeloid leukemia FAB subtype M1 (AML-M1). The karyotype, which has not changed significantly over several years of culture, was described initially as 44,XY,-5,del(7q),inv(7q),add(8q),