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Loss of retroviral gene expression in bone marrow reconstituted mice correlates with down-regulation of gene expression in long-term culture initiating cells

โœ Scribed by Lange, C; Blankenstein, T


Book ID
110037996
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
641 KB
Volume
4
Category
Article
ISSN
0969-7128

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## Abstract ## Background Gaucher disease is a lysosomal storage disorder resulting from a deficiency of glucocerebrosidase (GC). Recently, lentivirus vectors have been developed for efficient gene transfer into hematopoietic stem cells (HSCs). A recombinant lentivirus vector was used to evaluate