Loss of expression of ZAC/PLAGL1 in diff
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Elizabeth M. A. Valleley; Sarah F. Cordery; Ian M. Carr; Kenneth A. MacLennan; D
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Article
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2010
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John Wiley and Sons
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English
⚖ 278 KB
## Abstract __ZAC/PLAGL1__ is a ubiquitously expressed, imprinted tumor suppressor gene located on 6q24, a chromosomal region that is frequently deleted in diffuse large B‐cell lymphoma (DLBCL). Like p53, ZAC regulates cell cycle arrest and apoptosis concomitantly, and loss of expression is implica