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Loss of Power in Two-Stage Residual-Outcome Regression Analysis in Genetic Association Studies

โœ Scribed by Ronglin Che; Alison A. Motsinger-Reif; Chad C. Brown


Book ID
115556030
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
787 KB
Volume
aop
Category
Article
ISSN
0741-0395

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Bias due to two-stage residual-outcome r
โœ Serkalem Demissie; L. Adrienne Cupples ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 90 KB

Association studies of risk factors and complex diseases require careful assessment of potential confounding factors. Twostage regression analysis, sometimes referred to as residual-or adjusted-outcome analysis, has been increasingly used in association studies of single nucleotide polymorphisms (SN