## Abnormalities of the G 1 cell-cycle checkpoint are commonly reported in cancers at various anatomic sites. pRB, p16 INK4a and cyclin D1 are critical G 1 -checkpoint proteins responsible for maintaining the balance of cellular proliferation. We examined a series of 38 pediatric osteosarcomas for
Loss of p16INK4, alone and with overexpression of osteopontin, correlates with survival of patients with spinal metastasis from hepatocellular carcinoma
โ Scribed by Hua-jiang Chen; Jian-ru Xiao; Wen Yuan
- Book ID
- 107576950
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 265 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1357-0560
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND Intrahepatic metastasis via portal vein spread is an important feature and a crucial unfavorable prognostic factor of hepatocellular carcinoma (HCC). To identify the molecular factors for tumor progression, the authors used differential display (DD) to analyze aberrant ge
The molecular mechanisms of hepatocarcinogenesis recent study on potential familial HCC in Alaskan natives are poorly understood. Only very recently has there excluded mutation of the p53 gene as the responsible genetic been a suggestion of familial hepatocellular carcinoma lesion. 1 This suggests t