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Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

โœ Scribed by Pham, A. H.; Meng, S.; Chu, Q. N.; Chan, D. C.


Book ID
118247942
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
953 KB
Volume
21
Category
Article
ISSN
0964-6906

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## Abstract Nicotinic acetylcholine receptors (nAChR) are widely distributed in the central nervous system, where they exert a modulatory influence on synaptic transmission. For the striatum, pharmacological evidence supports the presence of presynaptic ฮฑ3ฮฒ2\* and ฮฑ4ฮฒ2\* nAChR that modulate dopamin