✦ LIBER ✦

Loss of material from chromosome arm 1p during malignant progression of meningioma revealed by fluorescent in Situ hybridization

✍ Scribed by Shinsuke Ishino; Naoya Hashimoto; Shinji Fushiki; Kousei Date; Toshiki Mori; Masahito Fujimoto; Yoshio Nakagawa; Satoshi Ueda; Tatsuo Abe; Johji Inazawa

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 355 KB
Volume: 83
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19980715)83:2<360::aid-cncr21>3.0.co;2-q

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND.

Atypical and anaplastic meningiomas tend to recur and to invade adjacent brain, bone, and skin. They also can metastasize to extracranial organs such as the lung, liver, or bone, causing death. Recent reports have indicated that allelic deletion of chromosome 1p is associated with malignant progression of meningiomas.