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Loss of Heterozygosity in Fibrocystic Change of the Breast: Genetic Relationship Between Benign Proliferative Lesions and Associated Carcinomas

✍ Scribed by Constance Washington; Fabienne Dalbègue; Fleurette Abreo; Jeffery K. Taubenberger; Jack H. Lichy

Book ID
117022268
Publisher
American Society for Investigative Pathology
Year
2000
Tongue
English
Weight
564 KB
Volume
157
Category
Article
ISSN
0002-9440

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Loss of heterozygosity on chromosome 9 i
Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions
✍ Gudny Eiriksdottir; Asgeir Sigurdsson; Jon Gunnlaugur Jonasson; Bjarni A. Agnars 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 801 KB

Primary breast tumors were tested for loss of heterozygosity (LOH), on chromosome 9p with microsatellite markers restricted to a 28 cM region including the MTSl gene. LOH was found with at least I marker in 38% of the 20 I cases analyzed. A high frequency of deletions was detected at the 9p23-pZI re