✦ LIBER ✦

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

✍ Scribed by Chappell, SA; Walsh, T; Walker, RA; Shaw, JA

Book ID: 109837472
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 891 KB
Volume: 76
Category: Article
ISSN: 0007-0920
DOI: 10.1038/bjc.1997.596

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stable amino-acid sequence of the Mannos

Stable amino-acid sequence of the Mannose-6-phosphate/insulin-like growth-factor-II receptor in ovarian carcinomas with loss of heterozygosity and in breast-cancer cell lines

✍ Jean-Marc Rey; Charles Theillet; Jean-Paul Brouillet; Henri Rochefort 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 143 KB 👁 2 views

The mannose-6-phosphate/insulin-like growth factor 2 receptor (Man-6-P/IGFII receptor) is involved in lysosomal enzyme sorting, IGFII degradation and pro-TGFbeta activation. Genetic alterations in hepatocarcinomas and a few breast cancers suggest that this receptor behaves as a tumor suppressor. Mor

Failure to detect genetic alteration of

Failure to detect genetic alteration of the mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) gene in hepatocellular carcinomas in japan

✍ Ikuo Wada; Hiroaki Kanada; Kimie Nomura; Yo Kato; Rikuo Machinami; Tomoyuki Kita 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 1 views

The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) suppresses cell growth through binding to the insulin-like growth factor 2 (IGF2) and latent complex of the transforming growth factor-␤ (TGF-␤). Recently, it was reported in the United States that loss of heterozygosity (LOH)