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Loss of heterozygosity and microsatellite instability in ductal carcinoma in situ of the breast

✍ Scribed by Y Ando; H Iwase; S Ichihara; S Toyoshima; T Nakamura; H Yamashita; T Toyama; Y Omoto; S Karamatsu; S Mitsuyama; Y Fujii; S Kobayashi


Book ID
117466568
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
404 KB
Volume
156
Category
Article
ISSN
0304-3835

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Microsatellite instability in ductal car
✍ Walsh, Tom; Chappell, Stephen A.; Shaw, Jacqui A.; Walker, Rosemary A. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 196 KB πŸ‘ 2 views

## Microsatellite instability (MI + ) is associated with defects in mismatch repair, resulting in a 'mutator' phenotype and the development and progression of cancer. MI + has been documented in invasive breast carcinomas. This study was undertaken to determine whether MI + is found in the early n