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Loss of heterozygosity analysis in uterine cervical adenocarcinoma

✍ Scribed by Kentaro Miyai; Yoshiaki Furugen; Toshiharu Matsumoto; Keiichi Iwabuchi; Sachiko Hirose; Katsuyuki Kinoshita; Hiroaki Fujii


Book ID
113959314
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
292 KB
Volume
94
Category
Article
ISSN
0090-8258

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## Abstract It is unclear which chromosome arms frequently show loss of heterozygosity (LOH) in adenocarcinoma of the uterine cervix. To identify such chromosomal arms, LOH on 52 different chromosome loci was examined using laser capture microdissection and PCR‐LOH analysis in 25 common‐type adenoc

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Uterine leiomyomas are extremely common, benign, smooth muscle tumors that represent a significant public health problem. Although there have been few molecular studies of uterine leiomyomas, most of them have reported a very low frequency of loss of heterozygosity (LOH) in different regions of the