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Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer

✍ Scribed by Yoshihiko Kitajima; Kohji Miyazaki; Shiroh Matsukura; Masayuki Tanaka; Mutsuo Sekiguchi

Book ID
106280828
Publisher
Springer
Year
2003
Tongue
English
Weight
552 KB
Volume
6
Category
Article
ISSN
1436-3291

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## Abstract ## Background hMLH1 and hMSH2 have been implicated to be involved in the DNA mismatch repair (MMR) system. The purpose of this study is to investigate the expression of hMLH1 and hMSH2 DNA MMR proteins in non‐small cell lung cancer (NSCLC) tissue and to elucidate their clinical signifi