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Loss of dorsal root ganglion cells concomitant with dorsal root axon sprouting following segmental nerve lesions

✍ Scribed by H.A. Lekan; K. Chung; Y.W. Yoon; J.M. Chung; R.E. Coggeshall

Book ID: 117491939
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 298 KB
Volume: 81
Category: Article
ISSN: 0306-4522
DOI: 10.1016/s0306-4522(97)00173-5

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The present study deals with changes in numbers and sizes of primary afferent neurons (dorsal root ganglion [DRG] cells) after sciatic nerve transection. We find that this lesion in adult rats leads to death of some DRG cells by 8 weeks and 37% by 32 weeks after the lesion. The loss of cells appears