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Loss of callosal fibre integrity in healthy elderly with age-related white matter changes

✍ Scribed by Martin Griebe; Alex Förster; Michèle Wessa; Christina Rossmanith; Hansjörg Bäzner; Tamara Sauer; Kathrin Zohsel; Christian Blahak; Andrea V. King; Julia Linke; Michael G. Hennerici; Achim Gass; Kristina Szabo

Publisher: Springer
Year: 2011
Tongue: English
Weight: 479 KB
Volume: 258
Category: Article
ISSN: 0340-5354
DOI: 10.1007/s00415-011-5956-6

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## Abstract Diffusion tensor imaging (DTI) measures diffusion of molecular water, which can be used to calculate indices of white matter integrity. Early DTI studies of aging primarily focused on two global measures of integrity; the average rate (mean diffusivity, MD) and orientation coherence (fr