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Loss of Bim results in abnormal accumulation of mature CD4−CD8−CD44−CD25− thymocytes

✍ Scribed by Jack Hutcheson; Harris Perlman


Book ID
116569232
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
655 KB
Volume
212
Category
Article
ISSN
0171-2985

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Ontogeny of T cell maturation in LEC mut
✍ Takashi Agui; Tohru Sakai; Kozo Matsumoto 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 421 KB 👁 1 views

## Abstract LEC rats bear a congenital deficiency in CD4^+^CD8^−^ thymocytes and peripheral CD4^+^ T cells, and consequently a deficiency in T~h~ cell functions. Ontogeny of T cell maturation in normal and LEC mutant rats was, therefore, investigated. Prenatal development of thymocytes in normal ra