Irinotecan (CPT-11) is a semisynthetic derivative of camptothecine that has proved activity in the treatment of colorectal carcinoma. The metabolites identiยฎed in humans include SN-38, SN-38 glucuronide, and several CYP3A-derived metabolites. We have studied the hepatic extraction, metabolism, and b
โฆ LIBER โฆ
Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver
โ Scribed by Peter J. Tobin; Ying Hong; J. Paul Seale; Laurent P. Rivory; Andrew J. McLachlan
- Book ID
- 119984182
- Publisher
- Pharmaceutical Press
- Year
- 2005
- Tongue
- English
- Weight
- 149 KB
- Volume
- 57
- Category
- Article
- ISSN
- 2042-7158
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