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Loop-sheet polymerization: the mechanism of alpha1-antitrypsin deficiency

โœ Scribed by D.A LOMAS

Book ID
117829328
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
338 KB
Volume
94
Category
Article
ISSN
0954-6111

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## Liver injury in PiZZ cY,-antitrypsin &-AT) deficiency probably results from toxic effects of the abnormal a,- AT molecule accumulating within the ER of liver cells.