Characterization of renal excretion mech
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Tomohiro Nishimura; Yukio Kato; Yoshimichi Sai; Takuo Ogihara; Akira Tsuji
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Article
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2004
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John Wiley and Sons
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English
โ 145 KB
M17055 was developed as a novel diuretic that inhibits both Na รพ , K รพ , and 2Cl ร cotransport at the thick ascending Henle's loop and Na รพ reuptake at the distal tubule. It is secreted at the renal proximal tubules. The purpose of the present study was to characterize the renal excretion mechanism