Longitudinal pet studies in families with chromosome 14 and 21 encoded Alzheimer's disease
โ Scribed by Parada, F.
- Book ID
- 124135662
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 173 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0197-4580
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Linkage studies in families with presenile onset of Alzheimer's disease (AD) indicated the presence of a predisposing gene on the proximal long arm of chromosome 21. We mapped four new loci in the candidate AD region using somatic cell hybrids. For three of the four loci, several restriction fragmen
This paper reviews data on the natural history of symptoms in patients with Alzheimer's disease (AD) and describes some of the problems encountered in analysing longitudinal data in this population. Data on cognition, functional ability and psychiatric or behavioural symptoms have all been obtained