✦ LIBER ✦

Longitudinal intrafascicular electrodes in collection and analysis of sensory signals of the peripheral nerve in a feline model

✍ Scribed by Li-Jun Li; Jian Zhang; Feng Zhang; William C. Lineaweaver; Tong-Yi Chen; Zhong-Wei Chen

Book ID: 102513648
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 120 KB
Volume: 25
Category: Article
ISSN: 0738-1085
DOI: 10.1002/micr.20159

No coin nor oath required. For personal study only.

✦ Synopsis

The purpose of this study was to evaluate the value of utilizing longitudinal intrafascicular electrodes (LIFEs) in collecting and analyzing sensory signals from the peripheral nerve. The longitudinal intrafascicular electrodes were made of 25-microm Teflon-insulated Pt/Ir wire and implanted into the fascicle of the superficial peroneal nerves in a feline model. The sensory signals at rest status and induced with various stimulations were recorded. The action potential area, frequency, coefficient of variation (CV) of the peak, and functional spectrum were then analyzed by the MF Lab version 3.01 software package. The results showed that the sensory nerve action potentials (SNAPs) were 0-2 spikes per second at rest state; the count was increased when stimulation was administered. SNAPs were 16-24 spikes per second when scraping stimulation was applied. The pulse intervals and the waveform remained consistent. SNAPs burst and were clustered when stress stimulation was given. The comparison of area, frequency, and CV of the peak showed statistically significant differences between these parameters receiving different stimulations. The functional spectrum analysis showed that the frequency of action potential increased when the stress stimulation was applied. In conclusion, LIFEs can sensitively collect sensory signals and provide a good interface to analyze sensory information from peripheral fasciculi. These data provide useful information for further study of control of electronic prostheses.

📜 SIMILAR VOLUMES

Longitudinally implanted intrafascicular

Longitudinally implanted intrafascicular electrodes for stimulating and recording fascicular physioelectrical signals in the sciatic nerve of rabbits

✍ Xiujun Zheng; Jian Zhang; Tongyi Chen; Zhongwei Chen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

## Abstract The purpose of this experiment was to determine the stimulating and recording characters of fascicular physioelectrical signals in the activity of peripheral nerves by longitudinally implanted intrafascicular electrodes (LIFEs) in a rabbit sciatic nerve model, and discuss the future app

Recording and stimulating properties of

Recording and stimulating properties of chronically implanted longitudinal intrafascicular electrodes in peripheral fascicles in an animal model

✍ Xiujun Zheng; Jian Zhang; Tongyi Chen; Zhongwei Chen 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB

## Abstract The purpose of this experiment was to study the recording and stimulating properties, and biocompatibility of longitudinally implanted intrafascicular electrodes (LIFEs) in a rabbit sciatic nerve model when they were chronically implanted into peripheral fascicles. LIFEs were implanted

Branching of sensory axons in the periph

Branching of sensory axons in the peripheral nerve of the rat

✍ Lauren A. Langford; Richard E. Coggeshall 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 615 KB

## Abstract The currently accepted concept of a primary sensory cell is a cell that gives rise to a central process which passes through the dorsal root to the spinal cord and a peripheral process which passes to the periphery via a peripheral nerve. If this is correct, then there should be equal n

A longitudinal, functional study of peri

A longitudinal, functional study of peripheral nerve recovery in the mouse

✍ Mike Yao; Michelle M. Inserra; Michael J. Duh; David J. Terris 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 580 KB

The distal sensory nerve action potentia

The distal sensory nerve action potential as a diagnostic tool for the differentiation of lesions in dorsal roots and peripheral nerves

✍ R. Benecke; B. Conrad 📂 Article 📅 1980 🏛 Springer 🌐 English ⚖ 514 KB

On the basis of the conception that, in preganglionic lesions, peripheral sensory nerve fibers should remain intact, the question arises whether evaluation of distal sensory nerve action potentials can be helpful in differentiating between cervical dorsal root and peripheral nerve lesions. Amplitude

Cellular expression of a leech netrin su

Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets

✍ Gan, Wen-Biao ;Wong, Victoria Y. ;Phillips, Aloysius ;Ma, Charles ;Gershon, Timo 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

Netrins are secreted, diffusible proteins that direct axonal growth. To study the functions of netrins in the relatively simple and easily accessible nervous system of the leech Hirudo medicinalis, we have cloned a leech netrin and have characterized its expression during embryogenesis. By probing a