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Longitudinal changes in IQ among fragile X females: A preliminary multicenter analysis

โœ Scribed by Fisch, Gene S. ;Simensen, Richard ;Arinami, Tadao ;Borghgraef, Martine ;Fryns, Jean-Pierre

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
418 KB
Volume
51
Category
Article
ISSN
0148-7299

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In prospective studies of young, fragile X [fra(X)] males with the full mutation, cognitive abilities (IQ scores) and adaptive behavior levels (DQ scores) declined in most subjects tested. Little is known about longitudinal changes in IQ and DQ scores in young fra(X) females, although one earlier re

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Longitudinal changes in IQ among mentally retarded (MR) fragile X [fra(x)] males have been reported previously. While age is associated with decline in IQ, not all males are so affected. This suggests that there may be more than one subtype of affected fra(X) male. Therefore, we examined the distrib