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Longitudinal analysis of the segregation of mtDNA mutations in heteroplasmic individuals

✍ Scribed by Neil Howell; Soumitra S Ghosh; Eoin Fahy; Laurence A Bindoff


Book ID
119470382
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
70 KB
Volume
172
Category
Article
ISSN
0022-510X

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Tissue segregation of a heteroplasmic mt
✍ P. Lertrit; A. S. Noer; E. Byrne; S. Marzuki πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 548 KB

The distribution of the causal 8344A-->G mtDNA mutation has been examined in six tissues of a patient with myoclonic epilepsy with ragged red fibers (MERRF), to study the developmental genetics of this type of mitochondrial disorder, and to determine the pathophysiological importance of the mtDNA he