Tissue segregation of a heteroplasmic mt
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P. Lertrit; A. S. Noer; E. Byrne; S. Marzuki
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Article
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1992
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Springer
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English
β 548 KB
The distribution of the causal 8344A-->G mtDNA mutation has been examined in six tissues of a patient with myoclonic epilepsy with ragged red fibers (MERRF), to study the developmental genetics of this type of mitochondrial disorder, and to determine the pathophysiological importance of the mtDNA he