Longevity and lifetime body weight in mice selected for rapid growth
β Scribed by EKLUND, J.; BRADFORD, G. E.
- Book ID
- 109703458
- Publisher
- Nature Publishing Group
- Year
- 1977
- Tongue
- English
- Weight
- 219 KB
- Volume
- 265
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/265048b0
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Mice selected for high (H6) and low (L6) 6-week body weight and a randombred control population (C1) were characterized for rate, composition and efficiency of growth. Individual body weights were obtained from birth to 8 weeks of age on 682 mice representative of the three lines. Individual whole c
Five generations of divergent selection for plasma concentration of insulin-like growth factor-1 (IGF-1) and for 12-week body weight were carried out in mice, including randomly selected control lines for each trait. All lines were replicated once (12 lines in total). Each replicate line consisted o
Background: Selection for body weight provides important animal models for studying mechanisms of growth regulation. This study evaluated growth responses of the gastrointestinal tract (GIT) to long-term selection of mice for high (H line) or low (L line) 8-week body weight as compared with random-b