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Long-term treatment of psoriasis with cyclosporin A—side-effects, minimal effective dose and cyclosporin blood levels

✍ Scribed by M. J. KORSTANJE; W.J.B.M. VAN DE STAAK

Book ID
108691943
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
174 KB
Volume
16
Category
Article
ISSN
0307-6938

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## Abstract Although cyclosporin A (CsA) and cortisone acetate (CRT) adversely affect bone, their combined effect on bone is unknown. Sprague Dawley rats were therefore administered either vehicle or CsA (7.5 mg/kg/day) by gavage and saline or CRT (2 mg/100 mg/day) by s.c. injection for 28 days. Gr