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Long-term stability of diluted solutions of the monoclonal antibody rituximab

โœ Scribed by Muriel Paul; Victoire Vieillard; Emmanuel Jaccoulet; Alain Astier


Book ID
118243851
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
708 KB
Volume
436
Category
Article
ISSN
0378-5173

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Long-term physico-chemical stability of
โœ Paul, Muriel; Vieillard, Victoire; Da Silva Lemos, Ricardo; Escalup, Laurence; A ๐Ÿ“‚ Article ๐Ÿ“… 2013 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 502 KB

Using several complementary analytical methods, we demonstrated that the monoclonal antibody Trastuzumab (Tz), diluted in 0.9% sodium chloride can be stored in polyolefin infusion bags at 4ยฐC or room temperature up to 6 months with no evidence of chemical or physical instability. No aggregation of T