Abstract
Background
The purpose of our study was to assess the long‐term results in the management of patients with esthesioneuroblastoma.
Methods
A total of 28 patients were retrospectively reviewed to analyze their clinical features, treatment outcomes, pattern of failures, and course of the disease.
Results
The patients were classified as 2 patients with T1, 10 patients with T2, 10 patients with T3, and 6 patients with T4; the results of all were included in this study. Twenty‐six patients underwent surgery and 23 had postoperative radiotherapy over the tumor bed, only 9 had radiotherapy over the nodes. The average follow‐up was 99.11 months. Fifteen‐year and 20‐year disease‐specific and disease‐free survival rates were 88.6% to 66.4% and 59.6% to 29.8%, respectively. Six patients had recurrences and 60% of them occurred more than 10 years after treatment. In the first decade, nodal recurrences appeared earlier than local ones when patients with N0 did not undergo neck irradiation.
Conclusion
Surgery on patients with T presentations and adjuvant radiotherapy on T and N0 neck presentations seem to be essential to treat esthesioneuroblastoma. A follow‐up for a minimum of 20 years is necessary to ensure complete cure. © 2010 Wiley Periodicals, Inc. Head Neck, 2011