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Long term response (LTR) to interferon monotherapy (IFN-Mon) revisited: unearthing interferon breakthrough in the age of ribavirin combination therapy for chronic hepatitis C

โœ Scribed by Massimo Pozzi; Alessandro Redaelli; Fabio Panizzuti; Giancarla Poli; Sergio Foresti; Laura Ratti; Elena Redaelli; Grazia Traverso; Alessandro Dallei; Alberto Piperno; Luigi Roffi; Giuseppe Mancia


Book ID
118565795
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
109 KB
Volume
36
Category
Article
ISSN
0168-8278

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Combination treatment with pegylated-interferon-alpha (PEG IFN-โฃ) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may