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Long-Term Prognosis of Haemangioblastoma of the CNS: Impact of von Hippel-Lindau Disease

✍ Scribed by M. Niemelä; S. Lemeta; P. Summanen; T. Böhling; M. Sainio; J. Kere; K. Poussa; R. Sankila; H. Haapasalo; H. Kääriäinen; E. Pukkala; J. Jääskeläinen

Book ID: 106206011
Publisher: Springer Vienna
Year: 1999
Tongue: English
Weight: 270 KB
Volume: 141
Category: Article
ISSN: 0001-6268
DOI: 10.1007/s007010050412

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A series of 20 capillary haemangioblastomas of the central nervous system was screened for mutations of the von Hippel-Lindau ( VHL) tumour suppressor gene by single strand conformational polymorphism (SSCP) and heteroduplex analysis. Aberrant polymerase chain reaction (PCR) products were detected i