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Long-term potentiation in the interpositus and vestibular nuclei in the rat

โœ Scribed by R. J. Racine; D. A. Wilson; R. Gingell; D. Sunderland

Book ID
104676236
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
406 KB
Volume
63
Category
Article
ISSN
0014-4819

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โœฆ Synopsis

Previous unpublished experiments from this laboratory had revealed only post-activation depression effects in the cerebellar cortex when its inputs were activated by high frequency trains. In the experiments reported in this paper, we found reliable long-term potentiation (LTP) effects in the deep nuclei (interpositus and vestibular) when stimulation trains were applied to the white matter at the point where inferior peduncle fibers enter the cerebellum. LTP effects were found in both acute and chronic preparations. In the chronic preparations, LTP lasted for at least 8 days in all but one animal.

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