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Long-term phenotypic correction of rodent hemiparkinsonism by gene therapy using genetically modified myoblasts

✍ Scribed by Cao, L; Zhao, Y-C; Jiang, Z-H; Xu, D-H; Liu, Z-G; Chen, S-D; Liu, X-Y; Zheng, Z-C


Book ID
110038595
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
183 KB
Volume
7
Category
Article
ISSN
0969-7128

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## Abstract ## Background A model for __in vivo__ gene therapy based on electroporation of human growth hormone (hGH)‐coding naked DNA in the muscle of dwarf (lit/lit) and immunodeficient dwarf (lit/scid) mice is described. ## Methods A plasmid containing the ubiquitin C promoter and the genomic