Long-term persistence of anti-HAV antibodies following active immunization with hepatitis A vaccine
✍ Scribed by H. Maiwald; W. Jilg; H.L. Bock; T. Löscher; F.v. Sonnenburg
- Book ID
- 117432696
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 314 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0264-410X
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To estimate the long-term persistence of anti-HAV antibodies, 120 (schedule 0-6) and 194 (schedule 0-12) adults were vaccinated and followed-up annually for 6 years. Shortly after the last dose, anti-HAV levels fell sharply (annual decline rate delta > 65%). Thereafter, delta diminished to 10-15%. G
## Abstract Long‐term persistence of vaccine‐induced immune response in adults was assessed annually for 15 years following primary immunization with a two‐dose inactivated hepatitis A vaccine. In 1992, 119 and 194 subjects aged 17–40 years and naïve for hepatitis A virus (HAV) were enrolled in two