✦ LIBER ✦

Long-term outcomes in pediatric liver transplantation

✍ Scribed by John Bucuvalas

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 154 KB
Volume: 15
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21915

No coin nor oath required. For personal study only.

✦ Synopsis

Critical clinical outcomes for pediatric liver transplantation (LT) recipients include (1) patient and graft survival, (2) complications (immune and nonimmune) of chronic immunosuppressive medications, and (3) long-term graft function. 2. Recurrence of malignancy, sepsis, and posttransplant lymphoproliferative disorder account for more than 65% of deaths occurring more than 1 year after LT. 3. Chronic rejection, late hepatic artery thrombosis, and biliary strictures account for 70% of graft loss occurring more than 1 year after LT. 4. Late histological changes in the allograft are emerging as a common problem in patients more than 5 years after LT. The pathogenesis of these findings and the impact on graft survival remain to be determined.

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