Long-term outcome of severe chronic plaque psoriasis following treatment with high-dose topical calcipotriol
✍ Scribed by Bleiker; Bourke; Mumford; Hutchinson
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 224 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0007-0963
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✦ Synopsis
We have previously reported the effectiveness of high-dose calcipotriol in extensive psoriasis. We now report the long-term outcome in patients following this treatment. Twenty-eight patients with severe psoriasis were treated as in-patients with high-dose topical calcipotriol for 2 weeks. There was a mean reduction in the psoriasis area and severity index of 65%. Sixty-nine per cent were controlled for 3 months and 42% for 6 months. The relapse rate was comparable with that following Ingram's regimen, the in-patient stay was shorter and the treatment more acceptable. Careful monitoring of calcium homeostasis is mandatory.