𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Long-term outcome of quetiapine use for psychosis among parkinsonian patients

✍ Scribed by Hubert H. Fernandez; Martha E. Trieschmann; Monica A. Burke; Carol Jacques; Joseph H. Friedman

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
64 KB
Volume
18
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

To evaluate the long‐term efficacy and tolerability of quetiapine for psychosis among parkinsonian patients, a retrospective analysis of all parkinsonian patients taking quetiapine for psychosis in a single movement disorders center was carried out. Demographic data, including type and severity of psychosis, presence of dementia, treatment response, before and after Unified Parkinson's Disease Rating Scale (UPDRS)‐motor scores and Hoehn and Yahr (H&Y) scale were obtained. One hundred six parkinsonian patients with a mean age of 76.6 years were on an average levodopa (L‐dopa) dose of 415 mg/d. Seventy‐eight of 106 (74%) remained on quetiapine for a mean duration of 15 months at an average dose of 60 mg per day. Eighty‐seven (82%) patients had partial or complete resolution of their psychosis whereas 19 (18%) patients had no improvement on quetiapine. Motor worsening was noted in 34 (32%) patients but was uncommonly sufficient to warrant quetiapine discontinuation. More quetiapine non‐responders were noted to be demented, delusional, and experienced threatening psychosis but only the presence of dementia remained significant on multivariate analysis (OR = 11.6; 95% CI = 1.4–92.9). Also, patients who developed motor worsening while on quetiapine tended to be more demented (P = 0.07). Β© 2003 Movement Disorder Society

πŸ“œ SIMILAR VOLUMES

Long-term outcomes of 600 living donor l
Long-term outcomes of 600 living donor liver transplants for pediatric patients at a single center
✍ Mikiko Ueda; Fumitaka Oike; Yasuhiro Ogura; Kenji Uryuhara; Yasuhiro Fujimoto; M πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 137 KB πŸ‘ 1 views

This report concerns the long-term outcome of living donor liver transplantation (LDLT) for pediatric patients at a single center. Between June 1990 and December 2003, a total of 600 LDLTs, including 568 primary transplantations and 32 retransplantations, were performed for pediatric patients, who w

Prognostic factors affecting long term o
Prognostic factors affecting long term outcome after liver resection for hepatocellular carcinoma : Results in a series of 100 Italian patients
✍ Mario Lise; Stefano Bacchetti; Pierpaolo Da Pian; Donato Nitti; Pier Luigi Pilat πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 112 KB πŸ‘ 2 views

## Background: Long term results after liver resection for hepatocellular carcinoma (hcc) are disappointing because the disease tends to recur. in this study, the authors assessed prognostic factors affecting long term outcome, in the hope that these factors might be used in selecting hcc patients

APRI-M6 for predicting long-term outcome
APRI-M6 for predicting long-term outcome of chronic hepatitis C patients after interferon-based therapy: More questions than answers
✍ Tung-Hung Su; Jia-Horng Kao; Ding-Shinn Chen πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 59 KB πŸ‘ 2 views

We recognize the confusing terminology but can confirm that the gene we cloned and sequenced from the mouse genomic library and therefore subsequently knocked out is definitely RegIIIbeta, which we also name as Reg-2 because it is the homolog of rat Reg-2. To clarify the terminology, Table compare