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Long-term instability of alkaloid production by stably transformed cell lines ofCatharanthus roseus

✍ Scribed by Serap Whitmer; Camilo Canel; Robert van der Heijden; Robert Verpoorte


Book ID
110435619
Publisher
Springer
Year
2003
Tongue
English
Weight
65 KB
Volume
74
Category
Article
ISSN
0167-6857

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Three unselected cell lines of C. roseus maintained on a growth-associated alkaloid production medium were studied over a period of 2 to 5.5 years for the stability of alkaloid production (serpentine and ajmalicine). Large fluctuations in the total alkaloid content of 20-day-old cells were found for