Long-term immunosuppression without corticosteroids after orthotopic liver transplantation: A positive therapeutic aim
β Scribed by Fraser, Gerald M. ;Grammoustianos, Konstantinos ;Reddy, Jayendravandan ;Rolles, Keith ;Davidson, Brian ;Burroughs, Andrew K.
- Book ID
- 102934111
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1996
- Tongue
- English
- Weight
- 524 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1074-3022
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Most of the focus of orthotopic liver transplantation (OLT) research, since its inception as a treatment for end-stage liver disease in 1968, has been on factors that influence short-term outcomes (specifically acute cellular rejection). Five-year survival after transplantation improved to 72% from
Our aim was to investigate the time-related changes in various parameters following orthotopic rat liver transplantation with (AOLT) and without (NOLT) arterial reconstruction in male Lewis rats. Body weight and biochemical parameters were measured weekly, and a liver biopsy was obtained at 4, 8, an