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Long-term imipramine treatment enhances locomotor and food intake suppressant effects of m-chlorophenylpiperazine in rats

โœ Scribed by Charanjit S. Aulakh; Robert M. Cohen; James L. Hill; Dennis L. Murphy; Joseph Zohar


Book ID
117958659
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
943 KB
Volume
91
Category
Article
ISSN
0007-1188

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Long-term lithium treatment in rats atte
โœ Charanjit S. Aulakh; Joseph Zohar; Krystyna M. Wozniak; James L. Hill; Dennis L. ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 553 KB

Administration of various doses of m-chlorophenylpiperazine (m-CPP, a 5-HT agonist) to rats produced dose-related decreases in food intake and locomotor activity. Long-term (21 25 days) but not short-term (3-7 days) lithium treatment attenuated m-CPP-induced decreases in food intake. However, neithe