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Long-term evaluation of degradation and foreign-body reaction of subcutaneously implanted poly(DL-lactide-?-caprolactone)

โœ Scribed by den Dunnen, W. F. A. ;Robinson, P. H. ;van Wessel, R. ;Pennings, A. J. ;van Leeuwen, M. B. M. ;Schakenraad, J. M.


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
424 KB
Volume
36
Category
Article
ISSN
0021-9304

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โœฆ Synopsis


The aim of this study was to evaluate the degra-within 12 months and that no lactide or โ‘€-caprolactone crystals dation and foreign-body reaction of poly(DL-lactide-โ‘€-capro-were formed. Furthermore, we conclude that the foreign-body lactone) PLA 85 CL 50 ) bars. This specific biomaterial is used for reaction of PLA 85 CL 50 is very mild. These properties make the the construction of nerve guides, which can be used in the amorphous copolymer of DL-lactide and โ‘€-caprolactone reconstruction of short nerve gaps. Subcutaneously im-(50:50) suitable for the construction of nerve guides.


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Long-term evaluation of functional nerve
โœ M.F. Meek; W.F.A. Den Dunnen; J.M. Schakenraad; P.H. Robinson ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 183 KB ๐Ÿ‘ 1 views

This study was performed to evaluate the long-term functional nerve recovery after reconstruction of a 10-mm gap in the sciatic nerve of the rat, with a thin-walled nerve guide, composed of a biodegradable copolymer of DL-lactide and -caprolactone [p(DLLA--CL)]. To evaluate both motor and sensory ne