Long-term evaluation of bone-titanium interface in rat tibiae using light microscopy, transmission electron microscopy, and image processing
✍ Scribed by Takeshita, Fumitaka ;Ayukawa, Yasunori ;Iyama, Shinji ;Murai, Kenji ;Suetsugu, Tsuneo
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 378 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0021-9304
No coin nor oath required. For personal study only.
✦ Synopsis
We conducted a 2-year histologic and histometric a poorly mineralized layer remained in some areas between evaluation of the tibial bone-titanium (Ti) implant interface the mature bone and the titanium, and the interposed amorin male rats. Thirty male 6-week-old rats were used in this phous zone was still observed. Occasionally, a 200-nm-thick study. They were divided into two groups: 15 for day 28 layer, thought to be cell remnant, was seen. As calculated and 15 for day 730. Microscopic observation at day 28 re-in an image-processing system analysis, the percent bone vealed that the newly formed bone around the implant al-contact and the thickness and area of the surrounding bone most surrounded the implant, but fibroblastlike cells were for the Ti implant at day 28 were 43.6%, 30.4 Ȑm, and 0.10 interposed in some histologic sections. At day 730, in con-mm 2 , respectively, and those at day 730 were 89.9%, 53.5 trast, such cells were rarely seen, and the bone around the Ȑm, and 0.19 mm 2 , respectively. In summary, although the implant presented a lamellar structure. Transmission elec-passage of time may affect bone maturity, interfacial cells tron microscopic observation at day 28 disclosed mature or remain at the bone-Ti interface as a uniform layer together poorly mineralized bone near the implant; however, an elec-with unmineralized bone.