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Long-term efficacy of autologous haematopoietic stem cell transplantation in multiple sclerosis at a single institution in China

✍ Scribed by Bing Chen, Min Zhou, Jian Ouyang, Rongfu Zhou, Jingyan Xu, Qiguo Zhang, Yonggong Yang, Yong Xu, Xiaoyan Shao, Li Meng, Jing Wang, Yun Xu, Xiushi Ni, Xueguang Zhang

Book ID
113056628
Publisher
Springer Milan
Year
2011
Tongue
English
Weight
183 KB
Volume
33
Category
Article
ISSN
1590-1874

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Long-term efficacy of autologous haemato
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✍ Bing Chen, Min Zhou, Jian Ouyang, Rongfu Zhou, Jingyan Xu, Qiguo Zhang, Yonggong πŸ“‚ Article πŸ“… 2011 πŸ› Springer Milan 🌐 English βš– 183 KB

Autologous haematopoietic stem cell transplantation (AHSCT) is a promising treatment for multiple sclerosis (MS) patients who have not adequately responded to conventional therapies. We retrospectively evaluated the safety and long-term clinical outcome of AHSCT in MS patients in China. Twenty-five

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Based on the good results of experimental transplantation in animal models of multiple sclerosis and of other autoimmune diseases, we have treated 24 patients suffering from chronic progressive multiple sclerosis with high-dose chemotherapy (BEAM regimen) followed by autologous blood stem cell rescu