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Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial

✍ Scribed by Jean Yves Reginster; Rita Deroisy; Lucio C Rovati; Richard L Lee; Eric Lejeune; Olivier Bruyere; Giampaolo Giacovelli; Yves Henrotin; Jane E Dacre; Christiane Gossett

Book ID
117276409
Publisher
The Lancet
Year
2001
Tongue
English
Weight
94 KB
Volume
357
Category
Article
ISSN
0140-6736

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## Abstract ## Objective To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment. ## Methods In this placebo‐controlled trial, obese women (n = 431)