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Long-term effect of electroshock treatment on the entry of calcium into the cerebroventricular fluid in the rat

✍ Scribed by Amiram I. Barkai

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 393 KB
Volume: 9
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490090208

No coin nor oath required. For personal study only.

✦ Synopsis

The rate of appearance (R,) of calcium (Ca) in the cerebroventricular compartment of urethane-anesthesized rats was determined by two methods: one is measurement of isotope dilution during ventricular-cisternal perfusion with artificial cerebrospinal fluid (CSF) containing 45Ca, the other is estimation of the rate of entry of 45Ca from plasma after rapid injection of tracer 45CaC12 intravenously. Electroshock treatment (EST) for 3 successive days resulted in a marked increase in the rate of entry of calcium from blood to CSF. The effect of EST on the permeability of the blood-CSF bamer to Ca could be observed even 24 hr after the generalized seizure induced by electroshock has terminated.

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