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Long-Term Culture and Fine Specificity of Human Cytotoxic T-Lymphocyte Clones Reactive with Human Immunodeficiency Virus Type 1

✍ Scribed by Bruce D. Walker, Charles Flexner, Karen Birch-Limberger, Laura Fisher, Timothy J. Paradis, Anna Aldovini, Richard Young, Bernard Moss and Robert T. Schooley


Book ID
123637581
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
984 KB
Volume
86
Category
Article
ISSN
0027-8424

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## Abstract ## Background A monoclonal antibody (mAb) 2F5 binds to the membrane‐proximal external region (MPER) of the transmembrane subunit gp41 of human immunodeficiency virus type 1 (HIV‐1) is known to broadly neutralize HIV‐1 strains. The Adenovirus type 5 vector (Ad5) has been widely applied