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Long-Term Comparison of Tacrolimus- and Cyclosporine-Induced Nephrotoxicity in Pediatric Heart-Transplant Recipients

โœ Scribed by Robert F. English; Stephen A. Pophal; Silviu-Alin Bacanu; Jay Fricker; Gerard J. Boyle; Demetrius Ellis; Kelly Harker; Robert Sutton; Susan A. Miller; Yuk M. Law; Frank A. Pigula; Steven A. Webbera,*

Book ID
114423498
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
179 KB
Volume
2
Category
Article
ISSN
1600-6135

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## Background: Long-term treatment with cyclosporine (csa) or tacrolimus (tac) results in chronic nephrotoxicity. transforming growth factor-beta (tgf-beta) and other pro-fibrogenic molecules have been known to contribute to this side effect. a comparison of intrarenal expression of tgf-beta and ot