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Long-term anti–tumor necrosis factor antibody therapy in rheumatoid arthritis patients sensitizes the pituitary gland and favors adrenal androgen secretion

✍ Scribed by Rainer H. Straub; Georg Pongratz; Jürgen Schölmerich; Frieder Kees; Thomas F. Schaible; Christian Antoni; Joachim R. Kalden; Hanns-Martin Lorenz


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
161 KB
Volume
48
Category
Article
ISSN
0004-3591

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## Abstract ## Objective Cardiovascular disease is the major cause of excessive mortality in rheumatoid arthritis (RA). Atherosclerosis and RA share similar inflammatory mechanisms that include involvement of tumor necrosis factor α (TNFα). Anti‐TNFα antibody improved endothelial function in RA pa