Long-term (5-year) antibody persistence following two- and three-dose regimens of a combined hepatitis A and B vaccine in children aged 1–11 years
✍ Scribed by Helen Marshall; Terry Nolan; Javier Díez Domingo; Lars Rombo; Etienne M. Sokal; Josep Marès; Josep M. Casanovas; Sherine Kuriyakose; Maarten Leyssen; Jeanne-Marie Jacquet
- Book ID
- 116962629
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 415 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0264-410X
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## Abstract Long‐term persistence of vaccine‐induced immune response in adults was assessed annually for 15 years following primary immunization with a two‐dose inactivated hepatitis A vaccine. In 1992, 119 and 194 subjects aged 17–40 years and naïve for hepatitis A virus (HAV) were enrolled in two
## Abstract A combined hepatitis A and B vaccine is available since 1996. Two separate open‐label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17–43 years who received three doses of the v