๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Long-range PCR facilitates the identification of PMS2-specific mutations

โœ Scribed by Mark Clendenning; Heather Hampel; Jennifer LaJeunesse; Annika Lindblom; Jan Lockman; Mef Nilbert; Leigha Senter; Kaisa Sotamaa; Albert de la Chapelle

Book ID
102260343
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
82 KB
Volume
27
Category
Article
ISSN
1059-7794

No coin nor oath required. For personal study only.

โœฆ Synopsis

The original article to which this Erratum refers was published in Human Mutation 27(5): 490-495 (2006).

On page 491 in Figure 1C, and on page 494 in Table 2, the c.736_741del6ins11 mutation results in the protein variant p.P246CfsX3. It was incorrectly written as p.P246CfsX7.

๐Ÿ“œ SIMILAR VOLUMES

Long-range PCR facilitates the identific
Long-range PCR facilitates the identification of PMS2-specific mutations
โœ Mark Clendenning; Heather Hampel; Jennifer LaJeunesse; Annika Lindblom; Jan Lock ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 222 KB

## Communicated by Graham R. Taylor Mutations within the DNA mismatch repair gene, ''postmeiotic segregation increased 2'' (PMS2), have been associated with a predisposition to hereditary nonpolyposis colorectal cancer (HNPCC; Lynch syndrome). The presence of a large family of highly homologous PM

Identification of Lynch syndrome mutatio
Identification of Lynch syndrome mutations in the MLH1โ€“PMS2 interface that disturb dimerization and mismatch repair
โœ Jan Kosinski; Inga Hinrichsen; Janusz M. Bujnicki; Peter Friedhoff; Guido Plotz ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 423 KB ๐Ÿ‘ 2 views

Missense alterations of the mismatch repair gene MLH1 have been identified in a significant proportion of individuals suspected of having Lynch syndrome, a hereditary syndrome that predisposes for cancer of colon and endometrium. The pathogenicity of many of these alterations, however, is unclear. A