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Long-range effects on dynamics in a temperature-sensitive mutant of trp repressor

✍ Scribed by Lihua Jin; June Wong Fukayama; István Pelczer; Jannette Carey


Book ID
115628929
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
393 KB
Volume
285
Category
Article
ISSN
0022-2836

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## Abstract Extensive environment‐dependent rearrangement of the helix‐turn‐helix DNA recognition region and adjacent L‐tryptophan binding pocket is reported in the crystal structure of dimeric __E. coli trp__ aporepressor with point mutation Leu75Phe. In one of two subunits, the eight residues imm