✦ LIBER ✦
Long-range 1H coupling interactions: Identification of different pathways by 2D NMR δ—δ correlated spectroscopy. Applications in structural analysis
✍ Scribed by N. Platzer; N. Goasdoue; D. Davoust
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 740 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
The simplest methods of 2D 6-6 correlated spectroscopy (COSY and COSY LR) allow the easy observation of long-range coupling interactions. It is shown how these methods can lead to the discrimination between different pathways across single bonds: 4J through coplanar or gauche arrangement of the bonds and ' J through a zig-zag pathway or bond proximity. Applications to configurational and conformational analysis of polycyclic compounds, a trimer of isophorone, two natural terpenoids (carotol and daucol) and four steroids, are presented.