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Long QT syndrome: reduced repolarization reserve and the genetic link

✍ Scribed by D. M. RODEN

Book ID
108862144
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
110 KB
Volume
259
Category
Article
ISSN
0954-6820

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Long QT syndrome (LQTS) is an inherited disease involving mutations in the genes encoding a number of cardiac ion channels and a membrane adaptor protein. Among the genes that are responsible for LQTS, KCNE1 and KCNE2 are members of the KCNE family of genes, and function as ancillary subunits of Kv